| 15 When the anemia has caused decreased oxygen delivery to the tissues it can cause• This include doing a complete blood count with RBC indices, a peripheral smear to visualize the size and shape of RBCs, evaluation of iron content of blood and iron carrying capacity of blood and bone marrow studies 15 | SIDEROBLASTIC ANEMIA On the basis of MCH and MCHC values, the Hemoglobin content of red cells is described as: Increased MCHC — Hyperchromic Normal MCHC — Normochromic Decreased MCHC — Hypochromic USES OF RED CELL INDICES Red Cell indices are mainly used to Classify the type of anemia as the complete picture of Red blood cells via red cell indices reveals the variation in Size and Hemoglobin content of RBCs and helps the pathologist to classify the type of anemia |
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| Blood Blood, as everyone knows, is the fluid that circulates throughout the body due to the pumping action of heart | Hematocrit is nowadays measured by an automated blood analyser |
The pigment in Red Blood Cells: Iron-containing pigment — Hemoglobin is present — helps in the transport of oxygen from the lungs to tissues and carbon dioxide from tissues back to the lungs.
21| Dacie and Lewis Practical Haematology | At one stage they remove these organelles except the ribosomal network that helps it in limited protein and hemoglobin synthesis 15 |
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| com Causes of high reticulocyte percentage Reticulocyte count in peripheral blood can go high when the bone marrow tries to produce more RBC in response to a high requirement 33 | Anemia due to drugs- Cephalosporins, penicillins, non-steroidal anti-inflammatory drugs NSAIDS , Quinine etc have been reported to cause haemolytic anemia 24 |
RBC Count RBC count is generally measured as number of cells per micro litre of blood.
9| com How is Anemia diagnosed? 15, 25 Microcytic anemia When the RBC size is decreased, the hemoglobin content of the RBC also decreases | To understand the composition of blood, it is easier to consider it as a liquid portion and the cellular portion |
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| Conversely, if the MCV is elevated above 100 fL, it can be diagnosed as macrocytic | This volume is regulated by the kidneys |
The main functions of blood include carrying nutrition to the tissues, removing the toxic and unwanted materials from tissues and transport of oxygen to and carbon dioxide from the tissues.