| DOI: Free PMC article Affiliations• Various transcriptional regulation mechanisms have been identified as the mode of action for estrogen, mainly the classical mechanism with direct DNA binding but also a nongenomic mode of action and one using tethered or indirect binding | Flavonoid antioxidants with 2- or 3-phenylchroman structures such as quercetin, kaempferol, myricetin, apigenin, and luteolin, constituents of fruits, vegetables, tea, and wine, which may reduce coronary disease and cancer, are described |
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| Natural products in food preservatives are preferable to synthetic compounds due to their lower volatility and stability and generally higher antioxidant potential | 1 Emeritus Professor of Cancer Research, University of Wales College of Medicine, Laurel Cottage, Castleton, Cardiff CF3 2UR, UK |
2 Anti-inflammation Research Institute, San Diego, CA 92093, USA.
1| The antioxidant properties of carotenoids, which are dietary natural pigments, have been studied in relation to breast cancer risk and an inverse association was found with plasma concentrations: higher levels mean lower risk | 3 Halberg Hospital and Research Institute, Civil Lines, Moradabad, UP 244001, India |
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| Model of nuclear and non-nuclear estrogen receptor action | Following the Great Oxygen Event some 2 |
Growth factors IGF, EGF can phosphorylate ER through membrane growth factor receptor GFR mediated intracellular signaling pathways P circles to regulate gene expression in the absence of ligand nuclear action.
3